What could be the reason why i wake up with swollen, puffy eyelids?

See eye doctor: Many reasons. Could be allergies. Take shower and wash hair before bed so hair product and allergens don't go on your pillow and into your eyes. Wash eye lids before bed with one drop of baby shampoo diluted in a half a cup of water and then hold a warm compress over the closed eyes for five minutes while waiting to see your doctor.

Could be allergy: There are several possible reasons. Are your eyelids itchy as well? Could be allergy to something in your sleeping environment such as your pillow, laundry detergent or make up remover you apply as you get ready for bed.