Philippines
A 53-year-old male asked:
I am diabetic for more than ten years. is there side effect in continious intake of metformin and glimepiride 2x a day? thanks
3 doctor answers • 4 doctors weighed in
Dr. Quang Nguyenanswered
Specializes in Endocrinology
No: As long as the medications are still keeping your numbers in check, there is no long term side effects. Glimepiride loses effectiveness over time requiring a change in regimen but if it's still working for you, then no harm done.
Created for people with ongoing healthcare needs but benefits everyone.
5.3k viewsAnswered >2 years ago
Dr. David Sneidanswered
Endocrinology 43 years experience
Potentially, but...: There are potential side effects of all medications -- but the side effects of poorly controlled diabetes (because you didn't take your medication properly) are millions of times greater and possibly fatal.
Created for people with ongoing healthcare needs but benefits everyone.
5.2k viewsAnswered >2 years ago
Dr. James Chuanswered
Endocrinology 27 years experience
Each patient unique: Long-term metformin use can cause vitamin B12 deficiency, which leads to anemia and nerve symptoms in hands/feet. Some patients also develop GI symptoms (diarrhea, nausea) even after tolerating metformin initially. Long term sulfonylurea use (such as glimepiride) can cause weight gain, hypoglycemia and faster burnout of pancreatic insulin. See a specialist about which drug regimen is best for you.
Created for people with ongoing healthcare needs but benefits everyone.
5.2k viewsReviewed >2 years ago
Last updated Feb 9, 2021
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