Why does cancer affect people so differently?

Not all the same: Cancer is a general term used to describe the uncontrolled growth of abnormal cells. Prognosis varies depending on the cancer type, it's location, how large it is, where it invades, and if there is regional or distant spread. Different cancer types respond differently to surgery, radiation, and systemic therapy. Patient age, co-morbidities, and performance status also impact prognosis.