Fluconazole allergic reaction?

Possible: Possible but somewhat rare. What is more likely is an adverse effect of Fluconazole - the difference is an allergic reaction is an escalating immune response, while an adverse reaction is an intolerance of the medication for other reasons. What were the symptoms?

Skin usually: Adverse reactions to Fluconazole are uncommon but can manifest in various ways, but usually involve skin reactions including mucus membranes like oral ulcers. Other organ systems that can be affected include nervous, heart, muscle, eye and kidney. I just saw a young lady with second episode of severe mouth and vaginal symptoms after Diflucan (fluconazole) dose. It happens.