Which is the most safest, effective, popular, and least side effect class bp medicine used long terms: ccb, bb, diuretics, arb, ace or other. thanks.?

Individualize: Your medicines needs to be individualized.A combination of an arb and hztc may be good.Ask your md!

Cannot answer: That cannot be answered. All of these classes of anti-hypertensives have side effects. It all depends on your other co-morbidities, your other medications for all other conditions, response to individual classes of medications, and side effects you may display to a class of medication based on genetics.