A member asked:

Could 10 mg isosorbide mono causes dependency.made my other bb& arb/hct bp med not work.noticed spikes until itake the iso mon again then bp goes down?

A doctor has provided 1 answer

No-nitrate tolerance: Oral nitrates can drop BP early after taking by dilating veins and reducing cardiac filling. If dehydrated this can cause light headedness. Should not affect other BP meds except in additive fashion. Will not make them less effective.

Answered 6/10/2014

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