A member asked:

What is the pathology of early/mild ulcerative colitis please?

3 doctors weighed in across 3 answers

Autoimmune process: Ulcerative colitis is a disease where the body attacks itself. The inner lining (mucosa) of the colon becomes pebbled with inflammation, causing poor absorption. The result, to the patient, is watery or bloody stool, at times with mucous in the stool as well. Uc is treated with steroids and other anti-inflammatory drugs, directed by a gastroenterologist. In late uc colon cancer could develop.

Answered 12/28/2012

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Dr. John Fung answered

Specializes in General Surgery

Ulcers in the colon: Ulcerative colitis is a chronic disease of the colon, in which the lining becomes inflamed and develops tiny ulcers. Uc is the result of an abnormal response by your body's immune system by sending white blood cells into the lining of the intestines, where they produce chronic inflammation and ulcerations. Uc can cause abdominal discomfort and frequent bowel movements and occasionally bleeding.

Answered 10/4/2016

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Chronic injury: Ulcerative colitis is distinguished from acute colitis by evidence of both acute and chronic mucosal injury. In early stages the chronic changes are mild gland architecture distortion and a pattern of chronic inflammation. Later, gland loss/branching and metaplasia occurs. The pathology can be similar to other processes so your doctor has to consider ALL the findings, to make the diagnosis.

Answered 12/30/2014

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