Are oral antibiotics the best treatment for a staph infection on the face?

See below: It depends what type of staph infection you are referring to. An abscess would need drainage. A cellulitis or soft tissue infection could be treated with oral antibiotics but if severe or associated with fever and toxicity intravenous antibiotics would be better until the sepsis was controlled. Mrsa infection would require different antibiotics than methicillin sensitive staph infection.