What is the definition or description of: psa, total with reflex to psa, free?

PSA: "prostate specific antigen" is a blood test to evaluate for prostate cancer. Psa comes essentially only from the prostate. It tends to increase with age, size of prostate and in prostate cancer. Free psa is only tested with total psa is between 4 and 10 ng/dl. A free psa that is low (<10) is concerning for cancer, when high (>25) is reassuring, and is not very helpful when between 10-25%.

Prostate specific : Prostate specific antigen is a protein produced by the cells of the prostate. When the level of psa is elevated in the blood, there is something wrong with the prostate, either an infection, a benign enlargement, or cancer. The psa protein may either be bound to a protein in the blood or unbound, hence called "free." the higher the percentage of free psa, the more likely the prostate is benign.

Prostate specific ag: Prostate specific antigen is a molecule made from prostate cells that is found in the bloods serum. It is normal for the normal baseline values to increase over the course of a mans aging life. However, depending on how fast or how high it goes it can represent other prostate issues. The free psa is a byproduct that is a bit more sensitive for certain things. The lower the free psa the worse.