In the pharma war among, warfarin, pradaxa, xarelto, eliquis(fda pending), which one is safest and most effective for cad/pad from a medical view?

Depends: Warfarin is cheaper, in the market for a long time. Disadvantages- many drug interactions and you have to frequently monitor your blood level with a protime or inr. The newer ones are expensive and are not covered by most of the insurance companies. Adv. - you don't need to get blood work frequently. Effectives for cad/pad, the newer agents are slightly better but stomach bleeding may be more.

Debatable: Warfarin is safe, but requires blood checks to make sure anticoagulation is within range. It also can be reversed in case of hemorrhage fairly easily. Pradaxa, xarelto, and Eliquis are called factor x inhibitors and don't require blood testing and are safe; however, they can't be reversed in case of an unexpected hemorrhage so there is some risk associated with them.