A member asked:

My methrotrexate i take for rhem arth is now contains preservatives. does this change the effectiveness? i don't think the medication is helping me as much as before.

3 doctors weighed in across 3 answers

Should : Should not make a difference but i would speak to a rheumatologist about this.

Answered 10/3/2016

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No, : No, the effectiveness should not be changed. Preservative is usually put into the larger multi-use vials of Methotrexate to reduce the risk of bacterial contamination but may not be in the smaller single-use vials as they are thrown away after a single injection.

Answered 10/3/2016

5.3k views

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The : The preservative will not decrease the effectiveness of methotrexate.

Answered 10/3/2016

5.3k views

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