What would cause a throbbing pain in the center of my hand? dull, sometimes sharp pain. pain is only in my hand, doesn't affect fingers.

Possible : Possible a nerve compression, a vascular aneurysm, for example.

Vascular lesions: This a very large differential. Vascular problems, orthopedics and neuromas are all in the differentiial.

Depends: Throbbing pain in the center of your hand can be caused by several conditions, including nerve irritation, circulatory issues, arthritis and tendonitis. If symptoms continue beyond a few days or so, see you primary doctor or a hand specialist for a complete evaluation.