A member asked:

How do breast cancer anti estrogen pills work?

4 doctors weighed in across 2 answers
Dr. Richard Orr answered

Specializes in Surgical Oncology

Starve tumor: Many tumors are fed by estrogen - the main female horomone. Anti-estrogen pills block the effects of estrogen (in a variety of different ways) and thereby starve the tumor from a vital growth factor. Even if you are postmenopausal (or even male) your body still produces estrogen in places like the adrenals and subcutaneous fat.

Answered 11/22/2012

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Aromatase inhibitor: An aromatase inhibitor blocks the conversion of testosterone like hormones in fat cells to the strong estrogen (estrone).

Answered 11/23/2012

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