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A member asked:
What is meant by having estrogen receptor positive breast cancer?
9 doctors weighed in across 3 answers
Hormone responsive: Er positive breast cancer means that the cancer expresses estrogen receptors. This is beneficial because we can hormonally manipulate this type of cancer with drugs like tamoxifen and Arimidex (anastrozole) which are antiestrogens.
Answered 1/12/2016
5.8k views
ER+: Estrogen receptors are small proteins found on the surface of some cancer cells. A positive result means the proteins are present, a negative result means they are not present.
Answered 8/8/2013
5.8k views
Feeds the cancer: Most breast cancers are estrogen receptor positive. The cancer cells have receptors that fit the estrogen molecule that a body produces. Think: a lock and key - when estrogen binds to the receptor the tumor cell is stimulated to grow and divide. Er+ tumors can be blocked by tamoxifen and Arimidex (anastrozole) (and others) that interfere with this pathway.
Answered 11/28/2017
5.8k views
Related Questions
A member asked:
Taking a multivitamin with 1 mg of boron in it. Read it can act as estradiol. My mother had estrogen positive breast cancer so should i not take this?
A doctor has provided 1 answer
A member asked:
Why do we give anti-estrogen drugs to post-menopausal women with breast cancer?
A doctor has provided 1 answer
A member asked:
Should a 65-year old woman with a family history of breast cancer continue estrogen?
13 doctors weighed in across 2 answers
A member asked:
If I have too much estrogen, or not enough progesterone, does that make me more susceptible to breast cancer?
3 doctors weighed in across 3 answers
A member asked:
Does the estrogen that my physician prescribes increase my chance for breast cancer?
8 doctors weighed in across 2 answers
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Is it ok to use lotion containing estrogen phytocytes if you are taking femara (letrozole) for ER positive breast cancer?
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