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A member asked:
How do lidocaine and novocaine differ?
3 doctors weighed in across 2 answers
Chemically: Lidocaine is an amide type of anesthetic while procaine (novocain) is an ester.
Answered 6/19/2019
5.5k views
Pharmacologically: The first anesthetic has an amide hydrophilic link on the hydrocarbon chain, the other has an ester link. They both have lipophilic rings which are "unsaturated!" tmi? Sorry! the first requires lower dosing, has a longer duration, but a shorter onset, of action. Both have different indications for use, pathways of metabolism, absorption and distribution...So, a lot! like more specifics? Fire away.
Answered 6/19/2019
5.5k views
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