A member asked:

My mom is suffered from breast cancer she is 52 years old and surgery is done i want to know what is mean by er, pr negative and her3+positive.?

7 doctors weighed in across 2 answers

Tumor Receptors: The estrogen-, progesterone-, and her2/neu receptors are proteins present on some women's breast cancer cells. Their presence/absence, along with the anatomic stage (tumor size, lymph node involvement) guide chemotherapy recommendations, including which drugs may be most effective. Unless your mother's tumor is very small, it is likely her oncologist will recommend chemorx, including herceptin (trastuzumab).

Answered 12/9/2013

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Dr. Travis Kidner answered

Specializes in Surgical Oncology

Receptors: Some breast cancers display receptors to the hormones estrogen and progesterone. If the cancers have these hormone receptors, certain drugs can be used to slow down their grow. Er/pr negative means that your mother's tumors do not display these receptors. Her2neu is a different target for a type of chemo. Your mother's breast cancer is positive, and may benefit from treatment. Speak with her docs.

Answered 10/31/2012

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