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A 22-year-old male asked:

My mom is suffered from breast cancer she is 52 years old and surgery is done i want to know what is mean by er, pr negative and her3+positive.?

2 doctor answers7 doctors weighed in
Dr. Barry Rosen
General Surgery 34 years experience
Tumor Receptors: The estrogen-, progesterone-, and her2/neu receptors are proteins present on some women's breast cancer cells. Their presence/absence, along with the anatomic stage (tumor size, lymph node involvement) guide chemotherapy recommendations, including which drugs may be most effective. Unless your mother's tumor is very small, it is likely her oncologist will recommend chemorx, including herceptin (trastuzumab).
Dr. Travis Kidner
Surgical Oncology 17 years experience
Receptors: Some breast cancers display receptors to the hormones estrogen and progesterone. If the cancers have these hormone receptors, certain drugs can be used to slow down their grow. Er/pr negative means that your mother's tumors do not display these receptors. Her2neu is a different target for a type of chemo. Your mother's breast cancer is positive, and may benefit from treatment. Speak with her docs.

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Last updated Dec 9, 2013

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