42 with history of 2 children with cleft lip and palate with cerbralpalsy i am pregnant and really worried about it what are my chance of a normal ?

Genetic counseling!: This sounds really like a syndromic hereditary trait. You must seek expert genetic counseling asap to determine your recurrence risk - but i fear it is high if you are reproducing with the same partner. Either or both of you may be carriers of balanced chromosomal translocations producing affected offspring.

Www.cleftline.org.: Or both parents could be carriers of an autosomal recessive disorder, or one parent could have an autosomal dominant disorder with variable expression. If the "cp" is hypotonic (low muscle tone), the children may have a connective tissue disorder.They do need a genetic evaluation. A 2nd-trimester high-resolution fetal ultrasound may show a cleft lip;3-d fus may be needed to see a cleft palate.