I had one child with clieft lip. what is the chance of having another cleft lip and palate?

Reference quotes 4%: If you haven't done so already it is often helpful to parents to explore the risks associated with pregnancy with their dr or a genetic counselor. The frequency of some unexpected outcome in any pregnancy approaches 4%. A detailed look at the family tree on both sides may help u . Your risk in a 2nd pregnancy would push your risk of a surprise higher than that 4% but the CP risk would stay at 4%.

Around 4%: Assuming you have no other clefts in the family, the chances of another child with cleft lip/palate is around 4%.