A member asked:

I take methotrixate for ra (for1year) , now i have developed endometrial thickening. could this be related? my last pap exam was normal 9 months ago.

3 doctors weighed in across 2 answers

Doubt connection: I hope you get good control with the methotrexate. While it is a powerful drug with some risks, the endometrial changes are not one of the noted side-effects. Your gynecologist will help you decide whether to get a tissue diagnosis. Good luck.

Answered 3/26/2013

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No: This is very likely unrelated to Methotrexate use.

Answered 6/28/2014

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