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A member asked:

I take 4 methotrexate 2.5mg weekly for ra. my dentist prescribed today amoxicillin 500mg, i read that there is serious interactions, is this true?

A doctor has provided 1 answer

Yes.: Talk to your doctor before using methotrexate together with amoxicillin. Medications like amoxicillin, especially when given at high dosages for infections, can sometimes increase the blood levels and effects of methotrexate. You may have increased side effects such as nausea, vomiting, mouth ulcers, and low blood cell counts.

Answered 3/22/2016

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