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A 37-year-old female asked:

Can an increase in igg + iga proteins in the blood (serum) cause an overflow and therefore protein in the urine?

2 doctor answers3 doctors weighed in
Dr. Robert Kwok
Pediatrics 34 years experience
If kidney diseased..: Kidneys can leak protein if the kidneys are diseased. Proteinuria is a very sensitive predictor of development of progressive renal insufficiency, particularly when looking at high molecular weight proteins such as immunoglobulin g (igg), as predictors of chronic kidney disease progression. In some cases, mild proteinuria can occur without kidney disease.
Dr. Gurmukh Singh
Pathology 50 years experience
No: IgG and IgA are too large to get filtered through a normal kidney.

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Last updated Jan 13, 2020


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