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Houston, TX
A 21-year-old male asked:

What does igg, iga, and c-reactive protein have to do with detecting celiac's? they are normal levels, no antibodies detected.

2 doctor answers2 doctors weighed in
Dr. Jordan Rush
Gastroenterology 14 years experience
Celiac: Certain celiac markers can be checked in the blood and these are typically antibody tests labeled as igg and iga. CRP is a nonspecific marker of inflammation. The blood tests are pretty good markers of celiac but the best test is a biopsy of the small intestine.
Dr. Jason Hemming
Gastroenterology 18 years experience
Nothing really: You need to produce IgA to use the most sensitive blood test that we use to screen for celiac which is ttg-iga ab. Other tests include ema, and dgp. Regular gliadin abs should not be used as they are not very sensitive. The gold standard is a biopsy from the duodenum (small intestine).

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Last updated Jan 12, 2015


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