It depends: It depends on why you're on the methylprednisolone, and other problems you may have. Please talk with your own physician about this. Xanax (alprazolam) is a powerful anti-anxiety medication. Methylprednisolone may affect the same liver enzymes that process xanax (alprazolam). Your doctor is familiar with your personal health conditions, and we on healthtap are not.
Answered 5/8/2016
5.6k views
Yes.: No significant interaction. There may be some theoretical concerns with mental function.
Answered 9/7/2019
5.6k views
Xanax/Prednisone: Steroids may slightly decrease level of Xanax, (alprazolam) depending on the dose.
Answered 10/13/2017
3.1k views
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