A member asked:

Can you take xanax (alprazolam) while taking methyprednisolone ?

8 doctors weighed in across 3 answers
Dr. Pamela Pappas answered

Specializes in Psychiatry

It depends: It depends on why you're on the methylprednisolone, and other problems you may have. Please talk with your own physician about this. Xanax (alprazolam) is a powerful anti-anxiety medication. Methylprednisolone may affect the same liver enzymes that process xanax (alprazolam). Your doctor is familiar with your personal health conditions, and we on healthtap are not.

Answered 5/8/2016

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Yes.: No significant interaction. There may be some theoretical concerns with mental function.

Answered 9/7/2019

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Dr. Alan Ali answered

Specializes in Psychiatry

Xanax/Prednisone: Steroids may slightly decrease level of Xanax, (alprazolam) depending on the dose.

Answered 10/13/2017

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