What is the best pain medication for tooth ache?

Ibuprofen/tylenol: Alternating 3 Ibuprofen with 2 tylenol (acetaminophen) at 3 hour intervals gives almost narcotic levels of pain relief without the complications of narcotics. Assuming you can tolerate Ibuprofen and don't exceed the maximum daily dosage for either medication, there is a synergystic effect.

Ibuprophen: Assuming you have no allergies or medical issues with any medications. Start with tylenol (acetaminophen), (acetaminophen) then Motrin = ibuprophen= advil, aspirin. Next level of pain medication is what your dentist recommends: tramadol, vicodin, tylenol (acetaminophen) with codiene, Aspirin with codeine. There is no one best medication. It is what works for the patients pain that the doctor is comfortable prescribing.

Depends: It depends how severe the pain is. Mild pain meds like Ibuprofen for mild tooth aches and stronger pain medications like narcotics for severe tooth pain.