What is the most effective treatment for niddm (non-insulin-dependent diabetes mellitus)?

Diet exercise oral : Along with diet and exercise, oral agents such as glipizide/glyburide followed by the addition of metformin if not controlled. Glimepiride is often the next step. Then pioglitazone and sitagliptin could be used after previous alternatives attempted.

Many options: The best treatment for type 2 diabetes is proper diet and regular exercise to keep your weight in the normal range. The evidence is overwhelming that this works (but hard to do or maintain). However, if your bs is still high despite good diet/exercise routine, the first drug to add is metformin. This has benefits beyond glucose control. After that, you can choose other options...

Behavior Change!: You must aggressively change your lifestyle. Mobile Health games can help. Physicians recommend water, increased veggie intake and walking 10k steps a day. Changing your behavior is HARD! Here is a health game that will help! Commit to tracking your nutrition and weighing in weekly. Losing just 10 pounds can reverse diabetic state. https://itunes.apple.com/us/app/personal-medicine+/id846379884?m