A member asked:

Are lisinopril and spironolactone good for high bp?

3 doctors weighed in across 2 answers
Dr. Tarek Naguib answered

Specializes in Nephrology and Dialysis

Yes, but: 2different mechanisms Lisinopril is a BP medicine but spironolactone is a water pill i.e. Indirect BP control by controlling the volume of fluids in the body. The combination needs to be used with caution if kidney disease.

Answered 3/20/2020

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Hi bp rx: Lisinopril inhibits vasoconstriction, protects the heart and kidneys and arteries. It can elevate potassium. Spironolactone reduces sodium retention. It is gentle. It can elevate potassium, too. Be careful with potassium foods. Have blood testing every few weeks. Monitor your bp yourself. This combo has risks with potassium and risk relates to dose and diet.

Answered 8/29/2014

3.8k views

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