HealthTap Online Primary Care Doctors Accepting New Patients
Book a video visit
HealthTap
Telehealth
A member asked:

Are lisinopril and spironolactone good for high bp?

3 doctors weighed in across 2 answers
Dr. Tarek Naguib answered

Specializes in Nephrology and Dialysis

Yes, but: 2different mechanisms Lisinopril is a BP medicine but spironolactone is a water pill i.e. Indirect BP control by controlling the volume of fluids in the body. The combination needs to be used with caution if kidney disease.

Dr Ali and another doctor agreed

Answered 3/20/2020

5.6k views

Thank

Hi bp rx: Lisinopril inhibits vasoconstriction, protects the heart and kidneys and arteries. It can elevate potassium. Spironolactone reduces sodium retention. It is gentle. It can elevate potassium, too. Be careful with potassium foods. Have blood testing every few weeks. Monitor your bp yourself. This combo has risks with potassium and risk relates to dose and diet.

Answered 8/29/2014

3.8k views

Thank

Related Questions

A member asked:

Is it better to separate and take furosemide, aldactone and lisinopril at different times. Does taking them together have any short comings. I still feel a little tiredness at times climbing long stirs an uphill. ?

A doctor has provided 1 answer

A member asked:

Please I would like to know why do have diarrhoea almost every month, it comes once I feel a kind of heaviness around my lower abdomen. I am hypertensive and on bp medications; lisinopril, furosemide and aldactone and clopidogrel. I eat healthy. ?

2 doctors weighed in across 2 answers

A member asked:

I was asked the reason for taking these medications; furosemide(1am 1 pm) and aldactone(water retention), clopidogrel(left heart enlargement from poor bp control), lisinopril 5mg bp. Can I take the 2 furosemide once at am with aldactone and others PM?

A doctor has provided 1 answer

A member asked:

I am on lisinopril 5mg, furosemide 40mg 2 daily, aldactone 12.5mg and clopidogrel 75mg. why is my HBP 135/105 suddenly from 115/75? what am I doing wrong?

A doctor has provided 1 answer

A member asked:

I know water pills can be prescribed together, but is taking them(furosemide, aldactone, lisinopril and clopidogrel) separately at different times a better option? And I do get diarrhoea, tiredness climbing uphill in the midst of taking them.

A doctor has provided 1 answer

People also searched for:

Can spironolactone (25mg) be taken together with lisinopril (5mg) or how can they be taking?
Been on lisinopril-HCTZ 20-12.5 for ten years, dermatologist says I produce too much aldactone hormone, should I switch to spironolactone 100mg?
Is there any interaction between these HBP meds; lisinopril, Spironolactone and clopidogrel and Beetroot recipes? Read that Beetroot juice can lower HBP, don't know how truthful that is. And wondering if eating it can make me suffer hypotension?
I'm on spironolactone, metformin & lisinopril. Im not on birth control - do those meds pose a risk to a pregnancy? (Not ttc now but it could happen)
On lisinopril/hctz 20/12.5mg for hypertension and spironolactone 50 mg foracnehow much potassium should i eat a day? And being on two diuretics safe?

Telemedicine

Primary Care
Manage Your Conditions
Women's Health
Children's Health
Men's Health
Senior Health
Wellness, Prevention & Lifestyle
Sexual Health
Mental & Behavioral Health
Travel Medicine
Urgent Care
Ask your question
Didn't find what you're looking for?

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.

Ask your question

More of what we treat

Allergies
Antibiotics
Asthma
High Blood Pressure
Prescriptions
Type 2 Diabetes
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.
HealthTap
HIPAA logo
HIPAASecure
Soc 2 Type 2 logo
SOC 2 Type 2Certified
JCAHO Accredited
JCAHOAccredited
Member App

Download HealthTap

Video visit and message your doctor

Member App QR Code
Play Store Member LinkApp Store Member Link

Questions?

+1 (888) 828-0841support@healthtap.com
LinkedInTwitter
HomeTermsPrivacyCookiesDMCAHealth TopicsDoctors DirectoryDoctor Q&A by Specialty
Copyright 2026 HealthTap, Inc.