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A 32-year-old male asked:

Increased joint pain, fatigue, muscle pain, light rash on face. positive ana 1:160 homogenous & 1:160 speckled. lupus? why two ana results?

1 doctor answer1 doctor weighed in
Dr. Gurmukh Singh
Pathology 50 years experience
One screening one: for the specific pattern. ANA is a general screening test. Speckled pattern is further refinement of the test, as there are multiple types of anti-nuclear antibodies. It may not be lupus. It requires multiple criteria to be met for the diagnosis. You should discuss it with the doctor who ordered the test. You may visit this site for info: https://www.researchgate.net/publication/276353307_2015_ACRSLICC_Revised_Criteria_for_Diagnosis_of_Systemic_Lupus_Erythematosus
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Dr. Gurmukh Singh
Pathology 50 years experience
Provided original answer
Wish you good health!
Dec 11, 2017
Last updated Dec 11, 2017

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