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A 40-year-old member asked:

What is the difference between hydroxyzine and diphenhydramine?

1 doctor answer4 doctors weighed in
Dr. Joram Seggev
Specializes in Internal Medicine - Allergy & Immunology
Older antihstamines: Both medications are sedating antihistamines. Diphenhydramine is available over the counter in many forms; the best known brand name is benadryl (diphenhydramine). Prescription strength is 50mg. Atarax is available only by prescription, generic name is Hydroxyzine chloride (there is also Hydroxyzine pamoate, vistaril). If one takes either medication, that person should not drive.
Last updated Dec 3, 2020
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