A member asked:

Why can hydroxyzine be used for anxiety but not diphenhydramine? both are antihistamines, one derived from the other, correct?

A doctor has provided 1 answer
Dr. Margret Rose Dellosso answered

Specializes in Clinical Psychology

Not same effects: In same class of drugs as Diphenhydramine but has antagonistic effects on several receptor sites in the brain which means it works to treat anxiety, mild depression and unhealthy thought processes.

Answered 7/14/2018

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