Mt Plymouth, FL
A 32-year-old female asked:

Why can hydroxyzine be used for anxiety but not diphenhydramine? both are antihistamines, one derived from the other, correct?

1 doctor answer1 doctor weighed in
Dr. Margret Rose Dellosso
Clinical Psychology 21 years experience
Not same effects: In same class of drugs as Diphenhydramine but has antagonistic effects on several receptor sites in the brain which means it works to treat anxiety, mild depression and unhealthy thought processes.
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Last updated Jul 14, 2018


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