My wife is suffering with spleen enalrgement and getting weekness, stomach ache oftenly, ?

Many causes: An enlarged spleen can be caused by many thinks including infectious mono, portal hypertension and leukemia. Your wife should see a doctor and get examined and have her blood counts checked.

Multiple problems!: You must take her to a doctor immediately. If none a available since it is a weekend call your primary and ask if er would be best alternative or maybe they have emergency appointments available. It sounds like she needs a ct at least and careful history and physical exam. These are symptoms you must not ignore. Do not listen to other peoples advice. Listen to professionals who have had.