A member asked:

What drugs are used in oral contious sedation for dental work? with family history of malignant hyperthermia is there a risk?

17 doctors weighed in across 6 answers

Yes, but managable: Typically, valium and versed is used in IV conscious sedation for dental treatment, though sometimes just oral meds may be used. Your family history of mh should be investigated and can be managed. I would recommend that you see an oral and maxillofacial surgeon instead of a general dentist.

Answered 5/18/2016

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Little to no risk: Most oral conscious sedation (key word here is "conscious") are in the benzodiazepene class of drugs such as xanax, (alprazolam) valium, and ativan. One in particular called Halcion is used often in oral conscious sedation for dental work because it has quite an amnesic effect. Basically you will be awake still and be able to maintain your own airway but you will remember little to none of the procedure.

Answered 6/25/2014

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Dr. David Stall answered

Specializes in Dentistry

Little to no risk: Because most dental sedation is done using the class of drugs known as benzodiazapines, you can rest easy about mh occurring with dental sedation techniques. Mh occurs more often using general anesthetic agents.

Answered 1/7/2019

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Dr. Orrin Ailloni-Charas answered

Specializes in Anesthesiology

Oral sedation: With benzodiazepines or narcotics should be fine. Make sure your dentist is aware you have a family history of mh.

Answered 9/6/2012

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Dr. Allan Hawryluk answered

Specializes in Dentistry

Many....but....: I personally consult with a board certified anesthesiologist before sedating any patients with a family history of malignant hyperthermia. Many drugs can be used but this has to be dealt with on a case by case basis. If there is a any probability of malignant hyperthermia occurring i will do the case with the medical anesthesiologist present.

Answered 5/17/2013

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Fairly low risk: The drugs typically used in dental sedation are not triggers for mh. With your history though, would suggest having a board certified anesthesiologist care for you to make sure you receive no triggering drugs. Another option is to be tested for mh to determine if you are susceptible. This would be useful information if you ever require general anesthesia in the future.

Answered 5/18/2013

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