Can the intake of tamoxifen for breast cancer affect our uterus ?

Yes.: Tamoxifen can stimulate the utermine lining, can cause abnormal menstrual type bleeding, and could be a risk factor for uternine cancer. The benefits far outweight the risks, though.Tamoxifen can also increase the risk of blood clots, but lowers osteoporosis risk.

Yes, it does: Yes! tamoxifen is a quirky drug! it binds to the estrogen receptor on cells, and in most places blocks the activity of estrogen. But in some places, including the uterus, tamoxifen turns on the receptor instead of turning it off. This causes the lining of the uterus to build up and get thick. This slightly increases the risk of uterine cancer, especially in older women.