A member asked:

If i have incontinentia pigmenti, will i pass it on to my children?

A doctor has provided 1 answer

Maybe: Incontinentia pigmenti is an x linked dominant disorder. Every woman has two x chromosomes (that's what makes her female). In this disorder, she has one x with the gene for the disease, and one normal x. Her eggs each have one x, either the one with disease or the one without. She therefore has a 50:50 chance of passing the disorder to her daughter. It is usually lethal when passed to males.

Answered 9/23/2012

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