Is it possible for cold / flu medicine to make your gums swell?

Possible: If someone is allergic to the medication. I have never run across this situation, but gums can swell for a variety of reasons. It also may be another cause and you are relating it to the cold/flu medicine. I recommend seeing your dentist.

No: Medicine will not make your gums swell. However, if you are rundown due to your illness and you have gum disease then the infection around you gums could become more active. When you fill better, it is important to get a good dental check-up.

Possible: Again, it's possible but not likely. Some medications do cause gum (gingival) enlargement which many patients sometime perceive or interpret as swelling. You may be noticing swelling now because you are sensitive to it and equating it to the cold medicine. Some patients report these symptoms when they have the flu! floss thoroughly and check with your dentist! warm regards, dr. C.

Very possible: Oral epithelium react to the pathogens that are responsible for colds/flu/and especially allergy. A general swelling of all the paranasal tissue can be common. In addition, when people feel sick, they very often do not keep up with the normal oral hygiene regime, and that can result in gum inflammation.