How can i reduce the mood swings and irritability of pms?

Multiple ideas: Some women benefit from antidepressants such as zoloft, prozac, and paxil (paroxetine). All need fresh, whole foods, consistent rest and exercise, and stress reduction. Some find relief through botanical medicines such as st. John's wort, black cohosh, and chasteberry, and nutrients such as evening primrose oil & magnesium. A trained classical homeopath may be able to prescribe helpfully for you, too.