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A 41-year-old member asked:

Explain the blindness from levels of high oxygen when given to a premature infant?

2 doctor answers2 doctors weighed in
Dr. Benjamin Nguyen
A Verified Doctoranswered
14 years experience
Oxygen free radicals: Oxygen in high concentrations cause oxygen to breakdown and form oxygen free radicals which can damage cells in the body. In premature infants, this can lead to what is called retinopathy of prematurity.
Dr. James Ferguson
Pediatrics 47 years experience
Environment: The environment that produces normal eyes is the womb.While in the womb, baby's eyes get about 60% blood oxygen content. Early work with premi's included putting them in "incubators" & piping in oxygen, hoping that they survived.Testing blood gasses was almost impossible, but when obtained,O2 use was geared at keeping above 90%.Now they keep it lower.The high blood oxygen triggered damage in some

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Last updated Aug 29, 2016


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