A member asked:

Lewy body dementia - does anyone know of any treatment for this disease?

4 doctors weighed in across 2 answers
Dr. Pamela Pappas answered

Specializes in Psychiatry

Few options: There are currently no fda-approved treatments specific for lewy body dementia (dlb). But given the severe cholinergic losses that occur in dlb, the frequent co-occurrence of alzheimer's disease pathology, and several small trials that suggest their effectiveness, cholinesterase inhibitors are the off-label treatment of choice. Exelon (rivastigmine) patch has shown some effectiveness for the cognitive decline.

Answered 6/25/2014

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Meds & Support!!: Dopamine meds for physical parkinsonism: Azilect (mao-b selective inhibitor) & sinemet +/- Comtan (stalevo (carbidopa and levodopa and entacapone) is both together). Tailor rx watching for side effects. Avoid Dopamine agonists (requip xl/mirapex er/neupro)--too side effect prone for lewy body patients. For dementia: namenda, paired with Exelon patch or aricept. For psychosis: seroquel or even clozaril. For excess sleepiness: nuvigil.

Answered 6/25/2014

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