A member asked:

Does someone know details about lewy body dementia? is it hereditary. do other family members need checking?

5 doctors weighed in across 3 answers
Dr. Sam Gandy answered

Brain degeneration: The late life dementias are often characterized by the names of the proteins that accumulate. Lewy body dementia is also known as a synucleinopathy because the protein that builds up is called synuclein. When synuclein forms clumps, those clumps are called lewy bodies. There is no genetic test for lewy body disease. The cause is unknown. Lewy bodies in the brainstem cause parkinson's.

Answered 7/3/2018

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Rarely no test known: Neurodegenerative d/o featuring milder physical parkinsonism than parkinson's disease typically. (slowed movements, stiff/rigid muscles & posture, possibly resting tremor). But with early dementia, often with associated psychosis (visual hallucinations, delusional thoughts), excessive sleepiness, depression/anxiety/apathy, & rbd. Rbd = rem behavior d/o, causing acting-out of dreams in rem sleep.

Answered 12/9/2013

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Dr. James Schlichting answered

Specializes in Medical Psychotherapy

The etiology (cause) of Lewy Body Dementia remains unknown. A patient presenting with dementia, psychosis, and features of parkinsonism should be evaluated for the disorder. In this type of case presentation the neurologist will look history of a family member with LBD or Parkinson's Disease, which does increase the potential risk of developing the disorder (no specific test re genetic risk)

Answered 4/16/2023

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