Yes: Tsh peaks around midnight and is higher in the early morning than in the afternoon. In a normal person these changes are quite small and were not even detected until the 3rd generation TSH test became available.
Answered 5/19/2018
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No clinical issue: While there can be some mild fluctuation in TSH detected by sensitive assay, this is of no clinical significance to the patient over the course of a day.
Answered 5/19/2018
5.5k views
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