A member asked:

What is the mechanism of action of lidocaine as a local anesthetic?

6 doctors weighed in across 2 answers

Nerves are blocked: Lidocaine temporarily blocks initiation and conduction of impulses in nerves. This means that the affected area of the body does not feel sensation. Depending on the concentration of Lidocaine that is used, movement is also partially or completely blocked. Sympathetic nerves are blocked too, which can cause lower blood pressure when Lidocaine is used in epidural anesthesia.

Answered 6/26/2014

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Dr. William Jenkins answered

Specializes in Anesthesiology

It blocks: The sodium channels that are necessary for nerve conduction thus blocking sensation, and motor muscle movement at higher concentrations, some nerves are harder to block than others.

Answered 4/29/2014

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Related Questions

A member asked:

Can anesthetic a such as lidocaine be an agonist for sertraline or serotonin?

2 doctors weighed in across 2 answers