A member asked:

Can antiinflammatory creams actually go through the skin and get higher doses to your ankle sprain, or do they get washed away by skin blood flow?

12 doctors weighed in across 4 answers
Dr. Ellen Wenzel answered

Specializes in Podiatry

Topical NSAIDs: These types of creams penetrate the skin for localized effect. There is very little systemic absorption.

Answered 4/14/2021

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Effective: Topical anti-inflammatory creams such as voltaren (diclofenac) gel can be very effective.

Answered 4/14/2021

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Creams can help: Anti-inflammatory cream can help because you avoid the side effects of stomach upset which can happen with oral medications. Unless there are stomach problems, oral medications are considered more effective at controlling inflammation. Range of motion and strengthening exercises may be more effective in an ankle sprain . Initially rest, ice compression (wraps) and elevation aids healing.

Answered 4/14/2021

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Absorbed: The medication gets absorbed by the skin not washed away and it will reach the area inflammed. Much the same way if you take tylenol (acetaminophen) in knows how to get to your headache. Topicals are quite effective in doing their job.

Answered 4/14/2021

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