A member asked:

Can a woman have a normal ca125 blood test and still have ovarian cancer?

8 doctors weighed in across 4 answers

Possibly: Not usually but there are more accurate tests now , like the ova-1 and if I do a ca-125 i combine it with an he-4 blood test. If you are worried obviously you need to also have an ultrasound and possible further testing and your gyn can refer to to a gyn oncology surgeon- that type of doctor has additional training to deal with pre-cancer and cancer and to rule them in or out.

Answered 8/21/2020

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Yes: Ca 125 is not a good cancer marker. If elevate with a cancer, it may be used to monitor the progress of the tumor and effectiveness of treatment.

Answered 9/4/2019

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Dr. Liawaty Ho answered

Specializes in Hematology and Oncology

Yes: Ca 125 is not sensitive nor specific. Yes, some ovarian cancer do not produce ca 125- thus, ca -125 is only useful as a toold to monitor- for somebody who unfortunately has ovarian cancer and the ca 125 level is elevated.

Answered 10/29/2014

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Ovarian cancer: Yes. Only 85% of ovarian cancers have an elevated ca 12 at presentation. Therefore, 15 of every 100 women with a diagnosis of ovarian cancer have a ca 125 within the normal range. Ca 125 is not a diagnostic test. But is used to follow the progress of chemotherapy.

Answered 9/4/2019

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