A 63-year-old member asked:
can i take cymbalta (duloxetine) and gabapentin together?
2 doctor answers • 5 doctors weighed in
Internal Medicine 42 years experience
Cymbalta/gabapentin: I think both could be taken together-both are indicated for neuropathic pain and both are not habit forming.
5774 viewsReviewed >2 years ago
Child Psychiatry 34 years experience
Yes: There is no particular reason why you couldn't, although both medicines can cause sedation, so you would want to be careful about that side effect.
5772 viewsReviewed >2 years ago
How does cymbalta (duloxetine) work differently from gabapentin for CIPN?
1 doctor answer • 1 doctor weighed in
A Verified Doctor answered
Different mechanism: Chemotherapy-induced peripheral neuropathy (CIPN) are often treated with neuropathic medicine (e.g. Gabapentin) or selective serotonin and norepinephrine reuptake inhibitor (Cymbalta/Duloxetine). Gabapentin works by mimic GABA receptors (mainly inhibitory receptors) in the synaptic pathway, reduce excitation of neurons. Duloxetine is believe to inhibit pro-inflammatory cytokines in the brain.
3805 viewsAnswered Apr 29, 2018
A 67-year-old female asked:
Can I take Cymbalta (duloxetine) with gabapentin?
2 doctor answers • 9 doctors weighed in
Psychiatry 25 years experience
2789 viewsReviewed >2 years ago
Last updated Dec 29, 2020
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