Oligoclonal banding found in csf not in blood. is there other diseases they are found in besides ms?

Good question: While oligoclonal bands are often found in the CSF of people with MS, they are also found in people with infection, inflammation, and sometimes in normal cases. By themselves, they are not supportive of anything. Combined with MRI, history and physical exam data, they can support the diagnosis of MS.

Many: Any infectious or immune disorder causing synthesis of immune globulins within the brain and spinal cord can result in presence of the bands. It may be instructive to consider, syphilis, sarcoidosis, HIV, Lyme disease, and subacute sclerosing pan encephalitis as alternative explanations.