A member asked:

2.8 oligoclonal bands igg in csf. zero serum bands in csf. why does mayo clinic standards require 4 oligoclonal igg csf for ms diagnosis?

A doctor has provided 1 answer

Other causes: Oligoclonal bands can be present in some other conditions such as infections and inflammation of the central nervous system. Increasing the threshold for diagnosing MS by requiring at least 4 oligoclonal bands, allows to exclude these other causes and diagnose MS with greater certainty.

Answered 2/26/2015

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