A member asked:

Which opioid has the highest affinity for mu-opioid receptors?

A doctor has provided 1 answer
Dr. Paul Grin answered

Specializes in Pain Management

Morphine & Methadone: Morphine, the prototype of opioid analgesics, is a full "pure" agonist of the mu receptor. Methadone, a synthetic mu agonist opioid, has pharmaceutical activity very similar to morphine.

Answered 11/27/2017

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