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A 34-year-old member asked:

Is taking metformin with pioglitazone and glimperide tablets safe for long time use?

1 doctor answer1 doctor weighed in
Dr. Thomas Knecht
A Verified Doctoranswered
32 years experience
Yes, unless: Hi. Yes, in general that 3-drug cocktail is safe. Exceptions would be metformin at a certain level of kidney disease, pioglitazone in heart failure, and glimepiride if it's causing hypoglycemia. That 3-drug regimen will likely lose efficacy over time. Keep your diabetes, blood pressure, and lipids tightly controlled. Don't smoke! Good luck!
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Last updated May 7, 2021

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