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A member asked:
Is mitochondrial disease passed down from the mother? if kiddo has it, does it mean mom has it too?
4 doctors weighed in across 2 answers
Yes: Hi. Mitochondrial disease may be passed on by the egg, but not sperm. If the kiddo has it, it came from the mother.
Answered 11/4/2014
3.6k views
Complex issue: It takes 2 events to create the mitochondrial dysfunction. First the vulnerable mitochondria come along in the egg (sperm can't bring it).Then the combination of DNA formed by sperm/egg must have the wrong instructions so the mitochondria don't work right. This way mom can be unaffected and have a kid with the disorder.
Answered 7/24/2017
607 views
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