Mri guided vacum assisted biopsy of6cm non mass in right breast. benign results but follow up in 6 mth concerned about false negative and accuracy ?

Mass in breast: While biopsy results are not always 100% (there can be sampling issues), if your radiologist or surgeon feels that they were sampling the right area, and did a good job of sampling, there should be little concern of a false negative result. Most pathology groups section the sample pretty well and look carefully at all the cores obtained from the biopsy procedure. Accuracy is pretty high as well.

The 6 month: follow up may simply be standard protocol. If the biopsy results, although benign, did not explain the MRI finding (discordance), the proper recommendation would be a repeat MRI biopsy or surgical excision, not 6 month follow up. False negatives are a concern in every type of biopsy, but sampling error would be highly unlikely when the area of abnormality was as large as 6cm.