A member asked:

Took nucynta (tapentadol) er yesterday at 4, can i take cymbalta today?

5 doctors weighed in across 2 answers
Dr. Manuel Lopez diaz answered

Specializes in Emergency Medicine

No interaction : There no interaction between Nucynta (tapentadol) ER and Cymbalta sometime for chronic pain conditions they are prescribed together .

Answered 4/17/2016

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Dr. Moshe Lewis answered

Specializes in Physical Medicine and Rehabilitation

Not recommended: There is a concern about serotonin syndrome in having these medications at the same time or even very close together.WHile we realize that this is a small risk, even taking the Nucynta (tapentadol) and cymbalta in such proximity increases the risk.Therefore, you should consult with your doctor regarding next steps but not dose these meds in the same week. Their chemistry, side effects and benefits overlap alot

Answered 11/24/2016

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