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A 22-year-old female asked:

Took nucynta (tapentadol) er yesterday at 4, can i take cymbalta today?

2 doctor answers5 doctors weighed in
Dr. Manuel Lopez diaz
Emergency Medicine 30 years experience
No interaction : There no interaction between Nucynta (tapentadol) ER and Cymbalta sometime for chronic pain conditions they are prescribed together .
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Moshe Lewis
Physical Medicine and Rehabilitation 27 years experience
Not recommended: There is a concern about serotonin syndrome in having these medications at the same time or even very close together.WHile we realize that this is a small risk, even taking the Nucynta (tapentadol) and cymbalta in such proximity increases the risk.Therefore, you should consult with your doctor regarding next steps but not dose these meds in the same week. Their chemistry, side effects and benefits overlap alot
Created for people with ongoing healthcare needs but benefits everyone.

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Last updated Nov 24, 2016

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